The American Association for Cancer Research is currently accepting applications for grants designed to help drive research advances in the treatment of bladder cancer, the fourth most commonly diagnosed cancer in men and the eighth in women.

The two-year AACR Henry Shepard Bladder Cancer Research Grants will provide up to $250,000 in total support for innovative cancer research projects designed to accelerate the discovery, development and application of new agents to treat bladder cancer. In an effort to unify laboratory and clinical work, laboratory-based projects must present plans with clinical collaborations indicating how the work will be translated into the clinic. Similarly, clinical studies must show how the work was derived from basic pre-clinical work and how the results will be channeled back to laboratory-based collaborators. Four grants will be awarded in 2008.

Independent investigators who are affiliated with any institution involved in cancer research, cancer medicine, or cancer-related biomedical science anywhere in the world may apply. In order to expand the breadth of bladder cancer research, there are no geographical, national or residency status requirements.

In 2008, approximately 68,810 individuals are expected to be diagnosed with cancer of the bladder, and approximately 14,100 people will die from this devastating disease. Despite the high incidence and mortality rate, bladder cancer is sometimes overshadowed by other, more familiar genitourinary cancers and often does not receive a proportionate level of attention from the scientific community and potential donors. In terms of funding and development of new treatments, bladder cancer ranks below many less common and less deadly cancers.

The 2008 AACR Henry Shepard Bladder Cancer Research Grants represent a partnership between the Henry H. Shepard Trust and the AACR. The trustees distributing the funds from the estate of Henry Shepard, a successful lawyer, chose to establish this grant with the AACR Foundation in memory of John King, Shepard's long-time attorney and financial advisor, who died from bladder cancer.

For more information on eligibility criteria, the application process and other details about the AACR Henry Shepard Bladder Cancer Research Grants, please visit, aacr/page14038.aspx . Applications for these grants should be filed electronically through the proposalCENTRAL website at https://proposalcentral.altum, Inquiries from investigators regarding this grant should be directed to Hanna Hopfinger at hanna.hopfingeraacr. The application deadline is July 25, 2008.

The mission of the American Association for Cancer Research is to prevent and cure cancer. Founded in 1907, AACR is the world's oldest and largest professional organization dedicated to advancing cancer research. The membership includes 28,000 basic, translational and clinical researchers; health care professionals; and cancer survivors and advocates in the United States and 80 other countries. AACR marshals the full spectrum of expertise from the cancer community to accelerate progress in the prevention, diagnosis and treatment of cancer through high-quality scientific and educational programs. It funds innovative, meritorious research grants. The AACR Annual Meeting attracts more than 17,000 participants who share the latest discoveries and developments in the field. Special conferences throughout the year present novel data across a wide variety of topics in cancer research, treatment and patient care. AACR publishes five major peer-reviewed journals: Cancer Research; Clinical Cancer Research; Molecular Cancer Therapeutics; Molecular Cancer Research; and Cancer Epidemiology, Biomarkers & Prevention. Its most recent publication and its sixth major journal, Cancer Prevention Research, is dedicated exclusively to cancer prevention, from preclinical research to clinical trials. The AACR also publishes CR, a magazine for cancer survivors, patient advocates, their families, physicians and scientists. CR provides a forum for sharing essential, evidence-based information and perspectives on progress in cancer research, survivorship and advocacy.

American Association for Cancer Research

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